Alprazolam 2 mg
INDICATIONS AND USAGE Anxiety Disorders: Alprazolam tablets are indicated for the management of anxiety disorder (a condition corresponding most closely to the APA Diagnostic and Statistical Manual [DSM-III-R] diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. Generalized anxiety disorder is characterized by unrealistic or excessive anxiety and worry (apprehensive expectation) about two or more life circumstances, for a period of six months or longer, during which the person has been bothered more days than not by these concerns. At least 6 of the following 18 symptoms are often present in these patients: Motor Tension (trembling, twitching, or feeling shaky; muscle tension, aches, or soreness; restlessness; easy fatigability); Autonomic Hyperactivity (shortness of breath or smothering sensations; palpitations or accelerated heart rate; sweating, or cold clammy hands; dry mouth; dizziness or light-headedness; nausea, diarrhea, or other abdominal distress; flushes or chills; frequent urination; trouble swallowing or ‘lump in throat’); Vigilance and Scanning (feeling keyed up or on edge; exaggerated startle response; difficulty concentrating or ‘mind going blank’ because of anxiety; trouble falling or staying asleep; irritability). These symptoms must not be secondary to another psychiatric disorder or caused by some organic factor. Anxiety associated with depression is responsive to alprazolam. panic disorder: Alprazolam is also indicated for the treatment of panic disorder, with our without agoraphobia. Studies supporting this claim were conducted in patients whose diagnoses corresponded closely to the DSM-III-R/IV criteria for panic disorder (see CLINICAL STUDIES). panic disorder (DSM-IV) is characterized by recurrent unexpected panic attacks, ie, a discrete period of intense fear or discomfort in which four (or more) of the following symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart, or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) chest pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded, or faint; (9) derealization (feelings or unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes. Demonstrations of the effectiveness of alprazolam by systematic clinical study are limited to four months duration for anxiety disorder and 4 to 10 weeks duration for panic disorder; however, patients with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit. The physician should periodically reassess the usefulness of the drug for the individual patient.
Physicians Total Care, Inc.
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HOW SUPPLIED Alprazolam Tablets, USP, are available as follows: 0.25 mg (Light yellow, oval, scored AL/0.25 one side; G on reverse) Bottles of 10 NDC 54868-2929-7 Bottles of 15 NDC 54868-2929-0 Bottles of 20 NDC 54868-2929-5 Bottles of 30 NDC 54868-2929-2 Bottles of 50 NDC 54868-2929-1 Bottles of 60 NDC 54868-2929-6 Bottles of 90 NDC 54868-2929-8 Bottles of 100 NDC 54868-2929-3 0.5 mg (Dark yellow, oval, scored AL/0.5 one side; G on reverse) Bottles of 10 NDC 54868-2930-0 Bottles of 20 NDC 54868-2930-7 Bottles of 30 NDC 54868-2930-3 Bottles of 50 NDC 54868-2930-2 Bottles of 60 NDC 54868-2930-4 Bottles of 90 NDC 54868-2930-5 Bottles of 100 NDC 54868-2930-1 Bottles of 120 NDC 54868-2930-9 1 mg (white, oval, scored AL/1.0 one side; G on reverse) Bottles of 20 NDC 54868-3005-4 Bottles of 30 NDC 54868-3005-2 Bottles of 60 NDC 54868-3005-3 Bottles of 90 NDC 54868-3005-7 Bottles of 100 NDC 54868-3005-1 Bottles of 120 NDC 54868-3005-8 2 mg (white, oblong, multi-scored A L one side, G 2 on reverse) Bottles of 30 NDC 54868-4663-2 Bottles of 60 NDC 54868-4663-5 Bottles of 75 NDC 54868-4663-7 Bottles of 90 NDC 54868-4663-1 Bottles of 100 NDC 54868-4663-6 Bottles of 120 NDC 54868-4663-4 Store at 20º to 25ºC (68º to 77ºF)[See USP controlled room temperature]. Dispense in a tight, light-resistant container as defined in USP. Keep container tightly closed. Manufactured by: ALPHAPHARM PTY. LTD. 15 Garnet Street, Carole Park. Qld. 4300 Australia 110/7 Revised October 2007 Distributed and Repackaged by: Physicians Total Care, Inc. Tulsa, OK 74146
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