NovoLog Dailymed

Patient Information

NovoLog (NŌ-vō-log) ^®

(insulin aspart [rDNA origin] injection)

What is NovoLog?

• NovoLog is a man-made insulin that is used to control high blood sugar in adults and children with diabetes mellitus. •

Who should not take NovoLog?

Do not take NovoLog if you:

• are having an episode of low blood sugar (hypoglycemia). •
• have an allergy to NovoLog or any of the ingredients in NovoLog. •

Before taking NovoLog, tell your healthcare provider about all your medical conditions including, if you are:

• pregnant, planning to become pregnant, or are breastfeeding. •
• taking new prescription or over-the-counter medicines, vitamins, or herbal supplements. •

Before you start taking NovoLog, talk to your healthcare provider about low blood sugar and how to manage it.

How should I take NovoLog?

• that come with your NovoLog. • Read theInstructions for Use
• Take NovoLog exactly as your healthcare provider tells you to. •
• You should eat a meal within 5 to 10 minutes after you take your dose of NovoLog. • NovoLog starts acting fast.
• Know the type and strength of insulin you take. change the type of insulin you take unless your healthcare provider tells you to. The amount of insulin and the best time for you to take your insulin may need to change if you take different types of insulin. • Do not
• Ask your healthcare provider what your blood sugars should be and when you should check your blood sugar levels. • Check your blood sugar levels.
• You may give another person an infection or get an infection from them. • Do not share your NovoLog FlexPen, FlexTouch or needles with another person.

What should I avoid while taking NovoLog?

While taking NovoLog do not:

• Drive or operate heavy machinery, until you know how NovoLog affects you. •
• Drink alcohol or use prescription or over-the-counter medicines that contain alcohol. •

What are the possible side effects of NovoLog?

NovoLog may cause serious side effects that can lead to death, including:

Signs and symptoms that may indicate low blood sugar include: Low blood sugar (hypoglycemia).

• dizziness or light-headedness •
• blurred vision •
• anxiety, irritability, or mood changes •
• sweating •
• slurred speech •
• hunger •
• confusion •
• shakiness •
• headache •
• fast heart beat •

Your insulin dose may need to change because of:

• change in level of physical activity or exercise •
• increased stress •
• change in diet •
• weight gain or loss •
• illness •

Other common side effects of NovoLog may include:

• low potassium in your blood (hypokalemia), reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions), skin thickening or pits at the injection site (lipodystrophy), weight gain, and swelling of your hands and feet. •

Get emergency medical help if you have:

• trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion. •

These are not all the possible side effects of NovoLog. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General information about the safe and effective use of NovoLog.

Medicines are sometimes prescribed for purposes other than those uled in a Patient Information leaflet. You can ask your pharmacist or healthcare provider for information about NovoLog that is written for health professionals. Do not use NovoLog for a condition for which it was not prescribed. Do not give NovoLog to other people, even if they have the same symptoms that you have. It may harm them.

What are the ingredients in NovoLog?

insulin aspart (rDNA origin) Active Ingredient:

glycerin, phenol, metacresol, zinc, disodium hydrogen phosphate dihydrate, sodium chloride and water for injection Inactive Ingredients:

Manufactured by:

Novo Nordisk A/S

DK-2880 Bagsvaerd, Denmark

For more information, go to www.novonordisk-us.com or call 1-800-727-6500.

This Patient Information has been approved by the U.S. Food and Drug Administration

Revised: 10/2013

For more information go to

www.novologflextouch.com

© 2002-2013 Novo Nordisk

PATIENT INSTRUCTIONS FOR USE

NovoLog (NŌ-vō-log) ^®

(insulin aspart [rDNA origin] injection)

10 mL vial (100 Units/mL, U-100)

Read this Instructions for Use before you start taking NovoLog and each time you get a refill. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment. ^®

Supplies you will need to give your NovoLog injection: ^®

• 10 mL NovoLog vial • ^®
• insulin syringe and needle •
• alcohol swab •

Preparing your NovoLog dose: ^®

• Wash your hands with soap and water. •
• Before you start to prepare your injection, check the NovoLog label to make sure that you are taking the right type of insulin. This is especially important if you use more than 1 type of insulin. • ^®
• NovoLog should look clear and colorless. use NovoLog if it is thick, cloudy, or is colored. • ^® Do not ^®
• use NovoLog past the expiration date printed on the label. • Do not ^®

Pull off the tamper resistant cap (See Figure A). Step 1:

Wipe the rubber stopper with an alcohol swab (See Figure B). Step 2:

Hold the syringe with the needle pointing up.Pull down on the plunger until the black tip reaches the line for the number of units for your prescribed dose (See Figure C). Step 3:

Push the needle through the rubber stopper of the NovoLog vial (See Figure D). Step 4: ^®

Push the plunger all the way in. This puts air into the NovoLog vial (See Figure E). Step 5: ^®

Turn the NovoLog vial and syringe upside down and slowly pull the plunger down until the black tip is a few units past the line for your dose (See Figure F). Step 6: ^®

• If there are air bubbles, tap the syringe gently a few times to let any air bubbles rise to the top (See Figure G). •

Slowly push the plunger up until the black tip reaches the line for your NovoLog dose (See Figure H). Step 7: ^®

Check the syringe to make sure you have the right dose of NovoLog . Step 8: ^®

Pull the syringe out of the vial’s rubber stopper (See Figure I). Step 9:

•   Giving your Injection:

• Inject your NovoLog exactly as your healthcare provider has shown you. Your healthcare provider should tell you if you need to pinch the skin before injecting. • ^®
• NovoLog can be injected under the skin (subcutaneously) of your stomach area, buttocks, upper legs or upper arms, infused in an insulin pump, or given through a needle in your arm (intravenously) by your healthcare provider. • ^®
• If you inject NovoLog ,change (rotate) your injection sites within the area you choose for each dose. use the same injection site for each injection. • ^® Do not
• If you use NovoLog in an insulin pump, you should change your insertion site every 3 days. The insulin in the reservoir should be changed at least every 6 days even if you have not used all of the insulin. • ^®
• If you use NovoLog in an insulin pump, see your insulin pump manual for instructions or talk to your healthcare provider. • ^®
• NPH insulin is the only type of insulin that can be mixed with NovoLog . mix NovoLog with any other type of insulin. • ^® Do not ^®
• NovoLog should be mixed with NPH insulin if it is going to be injected right away under your skin (subcutaneously). • ^® only
• NovoLog should be drawn up into the syringe you draw up your NPH insulin. • ^® before
• Talk to your healthcare provider if you are not sure about the right way to mix NovoLog and NPH insulin. • ^®

Choose your injection site and wipe the skin with an alcohol swab. Let the injection site dry before you inject your dose (See Figure J). Step 10:

Insert the needle into your skin. Push down on the plunger to inject your dose (See Figure K). Step 11: Needle should remain in the skin for at least 6 seconds to make sure you have injected all the insulin.

Pull the needle out of your skin. After that, you may see a drop of NovoLog at the needle tip. This is normal and does not affect the dose you just received (See Figure L). Step 12: ^®

• If you see blood after you take the needle out of your skin, press the injection site lightly with a •
• piece of gauze or an alcohol swab. rub the area.   Do not

After your injection:

• recap the needle. Recapping the needle can lead to a needle stick injury. • Do not
• Throw away empty insulin vials, used syringes, and needles in a sharps container or some type of hard plastic or metal container with a screw on cap such as a detergent bottle or empty coffee can. Check with your healthcare provider about the right way to throw away the container. There may be local or state laws about how to throw away used syringes and needles. Do not throw away used syringes and needles in household trash or recycling bins. •

How should I store NovoLog ? ^®

freeze NovoLog . use NovoLog if it has been frozen. Do not ^® Do not ^®

• Keep NovoLog away from heat or light. • ^®
• Store opened and unopened NovoLog vials in the refrigerator at 36 F to 46 F (2 C to 8 C). Opened NovoLog vials can also be stored out of the refrigerator below 86 F (30 C). • ^{® O O O O ® O O}
• Unopened vials may be used until the expiration date printed on the label, if they are kept in the refrigerator. •
• Opened NovoLog vials should be thrown away after 28 days, even if they still have insulin left in them. • ^®

General information about the safe and effective use of NovoLog ^®

• Always use a new syringe and needle for each injection. •
• Do not share syringes or needles. •
• Keep NovoLog vials, syringes, and needles out of the reach of children. • ^®

This Instructions for Use has been approved by the U.S. Food and Drug Administration.

Manufactured by:

Novo Nordisk A/S

DK-2880 Bagsvaerd, Denmark

. NovoLog is a registered trademark of Novo Nordisk A/S ^®

NovoLog is covered by US Patent Nos. 5,618,913, 5,866,538, and other patents pending. ^®

© 2002-2013 Novo Nordisk

For information about NovoLog contact: ^®

Novo Nordisk Inc.

800 Scudders Mill Road

Plainsboro, New Jersey 08536

1-800-727-6500

www.novonordisk-us.com

Revised: March 2013

PATIENT INSTRUCTIONS FOR USE

NovoLog ^® 3 mL PenFill cartridge (100 Units/mL, U-100) ^®

Before using the NovoLog cartridge ^®

• Talk with your healthcare provider for information about where to inject NovoLog (injection sites) and how to give an injection with your insulin delivery device. 1. ^®
• Read the instruction manual that comes with your insulin delivery device for complete instructions on how to use the PenFill cartridge with the device. 2. ^®

How to use the NovoLog cartridge ^®

• Just before using your NovoLog cartridge, check to make sure that you have the right type of insulin. This is especially important if you use different types of insulin. 1. Check your insulin. ^®
• The insulin should be clear and colorless. The tamper-resistant foil should be in place before the first use. If the foil has been broken or removed before your first use of the cartridge, or if the insulin is cloudy or colored, do not use it. Call Novo Nordisk at 1-800-727-6500. 2. Carefully look at the cartridge and the insulin inside it.
• well with soap and water. If you clean your injection site with an alcohol swab, let the injection site dry before you inject. Talk with your healthcare provider for guidance on injection sites and how to give an injection with your insulin delivery device. 3. Wash your hands
• Gather your supplies for injecting NovoLog . 4. ^®
• Insert a 3 mL cartridge into your Novo Nordisk 3 mL PenFill cartridge compatible insulin delivery device. Wipe the front rubber stopper of the 3 mL PenFill cartridge with an alcohol swab, then attach a new needle. For NovoFine needles, remove the big outer needle cap and the inner needle cap. Always use a new needle for each injection to prevent infection. 5. ^{® ® ®}

Giving the airshot before each injection:

To prevent the injection of air and to make sure insulin is delivered, you must do an airshot before each injection. Hold the device with the needle pointing up and gently tap the PenFill cartridge holder with your finger a few times to raise any air bubbles to the top of the cartridge. Do the airshot as described in the device instruction manual. ^®

Giving the injection

6. Dial the number of units on the insulin delivery device that you need to inject. Inject the right way as shown to you by your healthcare provider.

7. Insert the needle into the skin. Inject the dose by pressing the push button all the way in. Keep the needle in the skin for at least 6 seconds, and keep the push button pressed all the way in until the needle has been pulled out from the skin. This will make sure that the full dose has been given. You may see a drop of NovoLog at the needle tip. This is normal and has no effect on the dose you just received. If blood appears after you take the needle out of your skin, press the injection site lightly with a finger. ^® Do not rub the area.

After the injection

8. Recapping can lead to a needle stick injury. Do not recap the needle.

9. Remove the needle from the PenFill cartridge after each injection. Keep the 3 mL PenFill cartridge in the insulin delivery device. The needle should not be attached to the 3 mL PenFill cartridge during storage. This will prevent infection or leakage of insulin and will help ensure that you receive the right dose of NovoLog . ^{® ® ® ®}

10. Put the used needle and cartridge in a sharps container, or some type of hard plastic or metal container with a screw on top such as a detergent bottle or coffee can. Check with your healthcare provider about the right way to throw away used needles and cartridges. There may be local or state laws about how to throw away used needles and syringes. Do not throw used needles and cartridges in household trash or recycling bins.

11. Put the pen cap back on the Novo Nordisk 3 mL PenFill cartridge compatible insulin delivery device. ^®

Date of Issue: March 2013

Version: 9

Novo Nordisk , NovoLog , PenFill , and NovoFine are registered trademarks of Novo Nordisk A/S. ^{® ® ® ®}

NovoLog is covered by US Patent Nos. 5,618,913, 5,866,538, and other patents pending. ^®

PenFill is covered by US Patent No. 5,693,027. ^®

© 2002-2013 Novo Nordisk

Manufactured by:

Novo Nordisk A/S

DK-2880 Bagsvaerd, Denmark

For information about NovoLog contact: ^®

Novo Nordisk Inc.

800 Scudders Mill Road

Plainsboro, New Jersey 08536

PATIENT INSTRUCTIONS FOR USE

NovoLog (NŌ-vō-log)FlexTouch Pen ^{® ®}

(insulin aspart [rDNA origin] injection)

• containing 300 units of U-100 NovoLog (insulin aspart [rDNA origin] injection) insulin. You can inject from 1 to 80 units in a single injection. • NovoLog FlexTouch Pen (“Pen”) is a prefilled disposable pen
• • Do not share your NovoLog FlexTouch Pen with another person. You may give an infection to them or get an infection from them.
• • This Pen is not recommended for use by the blind or visually impaired without the assistance of a person trained in the proper use of the product.

Supplies you will need to give your NovoLog injection:

• NovoLog FlexTouch Pen •
• a new NovoFine or NovoTwist needle •
• alcohol swab •
• 1 sharps container for throwing away used Pens and needles. • See “Disposing of used NovoLog FlexTouch Pens and needles” at the end of these instructions.

Preparing your NovoLog FlexTouch Pen:

• Wash your hands with soap and water. •
• • Before you start to prepare your injection, check the NovoLog FlexTouch Pen label to make sure you are taking the right type of insulin. This is especially important if you take more than 1 type of insulin.
• NovoLog should look clear and colorless. use NovoLog if it is thick, cloudy, or is colored. • Do not
• use NovoLog past the expiration date printed on the label or 28 days after you start using the Pen. • Do not
• • Always use a new needle for each injection to help ensure sterility and prevent blocked needles.

Step 1:

• Pull Pen cap straight off (See Figure B). •

(Figure B)

Step 2:

• (See Figure C). NovoLog should look clear and colorless. use it if it looks cloudy or colored. • Check the liquid in the Pen Do not

(Figure C)

Step 3:

• • Select a new needle.
• Pull off the paper tab from the outer needle cap (See Figure D). •

(Figure D)

Step 4:

• Push the capped needle straight onto the Pen and twist the needle on until it is tight (See Figure E). •

(Figure E)

Step 5:

• Pull off the outer needle cap. throw it away (See Figure F). • Do not

(Figure F)

Step 6:

• Pull off the inner needle cap and throw it away (See Figure G). •

(Figure G)

Priming your NovoLog FlexTouch Pen:

Step 7:

• Turn the dose selector to (See Figure H). • select 2 units

(Figure H)

Step 8:

• Hold the Pen with the needle pointing up. Tap the top of the Pen gently a few times to let any air bubbles rise to the top (See Figure I). •

(Figure I)

Step 9:

• Press and hold in the dose button until the dose counter shows “0”. The “0” must line up with the dose pointer. • Hold the Pen with the needle pointing up.
• A drop of insulin should be seen at the needle tip (See Figure J). •
  • If you see a drop of insulin, repeat steps 7 to 9, no more than 6 times. • do not
  • If you see a drop of insulin, change the needle and repeat steps 7 to 9. • still do not

(Figure J)

Selecting your dose:

Step 10:

• The dose pointer should line up with your dose (See Figure K). • Turn the dose selector to select the number of units you need to inject.
  • If you select the wrong dose, you can turn the dose selector forwards or backwards to the correct dose. •
  • The numbers are printed on the dial. • even
  • The numbers are shown as lines. • odd

(Figure K)

• The NovoLog FlexTouch Pen insulin scale will show you how much insulin is left in your Pen (See Figure L). •
• • To see how much insulin is left in your NovoLog FlexTouch Pen:
  • Turn the dose selector until it stops. The dose counter will line up with the number of units of insulin that is left in your Pen. If the dose counter shows 80, there are units left in your Pen. • at least 80
  • If the dose counter shows the number shown in the dose counter is the number of units left in your Pen. • less than 80,

(Figure L)

Giving your injection:

• Inject your NovoLog exactly as your healthcare provider has shown you. Your healthcare provider should tell you if you need to pinch the skin before injecting. •
• NovoLog can be injected under the skin (subcutaneously) of your stomach area (abdomen), buttocks, upper legs (thighs) or upper arms. •
• Change (rotate) your injection sites within the area you choose for each dose. use the same injection site for each injection. • Do not

Step 11:

• Choose your injection site and wipe the skin with an alcohol swab. Let the injection site dry before you inject your dose (See Figure M). •

(Figure M)

Step 12:

• (See Figure N). • Insert the needle into your skin
  • cover it with your fingers, this can stop your injection. • Make sure you can see the dose counter. Do not

(Figure N)

Step 13:

• (See Figure O). • Press and hold down the dose button until the dose counter shows “0”
  • The “0” must line up with the dose pointer. You may then hear or feel a click. •

(Figure O)

• the dose counter has returned to “0” and (See Figure P). • Keep the needle in your skin after slowly count to 6

(Figure P)

•  
  • • When the dose counter returns to “0”, you will not get your full dose until 6 seconds later.
  • • If the needle is removed before you count to 6, you may see a stream of insulin coming from the needle tip.
  • • If you see a stream of insulin coming from the needle tip you will not get your full dose. If this happens you should check your blood sugar levels more often because you may need more insulin.

Step 14:

• (See Figure Q). • Pull the needle out of your skin
  • If you see blood after you take the needle out of your skin, press the injection site lightly with a piece of gauze or an alcohol swab. rub the area. • Do not

(Figure Q)

Step 15:

• (See Figure R). • Carefully remove the needle from the Pen and throw it away
  • recap the needle. Recapping the needle can lead to needle stick injury. • Do not

(Figure R)

• If you have a sharps container, carefully slip the needle into the outer needle cap (See Figure S). Safely remove the needle and throw it away as soon as you can. • do not

(Figure S)

•  
  • store the Pen with the needle attached. Storing without the needle attached helps prevent leaking, blocking of the needle, and air from entering the Pen. • Do not

Step 16:

• Replace the Pen cap by pushing it straight on (See Figure T). •

(Figure T)

After your injection:

• Put your used NovoLog FlexTouch Pen and needles in a FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) loose needles and Pens in your household trash. •
• If you do not have a FDA-cleared sharps disposal container, you may use a household container that is: •
  • made of a heavy-duty plastic •
  • can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out •
  • upright and stable during use •
  • leak-resistant •
  • properly labeled to warn of hazardous waste inside the container •
• When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and syringes. For more information about the safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at: . • http://www.fda.gov/safesharpsdisposal
• Do not dispose of your used sharps disposal container in your household trash unless your community guidelines permit this. Do not recycle your used sharps disposal container. •

How should I store my NovoLog FlexTouch Pen?

• Store unused NovoLog FlexTouch Pens in the refrigerator at 36°F to 46°F (2°C to 8°C). •
• Store the Pen you are currently using out of the refrigerator below 86°F. •
• freeze NovoLog. use NovoLog if it has been frozen. • Do not Do not
• Keep NovoLog away from heat or light. •
• Unused Pens may be used until the expiration date printed on the label, if kept in the refrigerator. •
• The NovoLog FlexTouch Pen you are using should be thrown away after 28 days, even if it still has insulin left in it. •

General Information about the safe and effective use of NovoLog.

• • Keep NovoLog FlexTouch Pens and needles out of the reach of children.
• use a new needle for each injection. • Always
• share Pens or needles. • Do not

This Instructions for Use has been approved by the U.S. Food and Drug Administration.

Manufactured By:

Novo Nordisk A/S

DK-2880 Bagsvaerd, Denmark

Revised: 10/2013

PATIENT INSTRUCTIONS FOR USE

NovoLog FlexPen ^{® ®}

Introduction

Please read the following instructions carefully before using your NovoLog FlexPen . ^{® ®}

NovoLog FlexPen is a disposable dial-a-dose insulin pen. You can select doses from 1 to 60 units in increments of 1 unit. NovoLog FlexPen is designed to be used with NovoFine needles. ^®

• NovoLog FlexPen should not be used by people who are blind or have severe visual problems without the help of a person who has good eyesight and who is trained to use the NovoLog FlexPen the right way.   ^Δ

Getting ready

Make sure you have the following lis:

• NovoLog FlexPen •
• New NovoFine needle •
• Alcohol swab •

Preparing Your NovoLog FlexPen

Wash your hands with soap and water. Before you start to prepare your injection, check the label to make sure that you are taking the right type of insulin. This is especially important if you take more than 1 type of insulin. NovoLog should look clear.

. Pull off the pen cap (see diagram A). A

Wipe the rubber stopper with an alcohol swab.

B. Attaching the needle

 Remove the protective tab from a disposable needle.

Screw the needle tightly onto your FlexPen. It is important that the needle is put on straight (see diagram B).

Never place a disposable needle on your NovoLog FlexPen until you are ready to take your injection.

Pull off the big outer needle cap (see diagram C). C.

Pull off the inner needle cap and dispose of it (see diagram D). D.

• Always use a new needle for each injection to help ensure sterility and prevent blocked needles.   Δ
• Be careful not to bend or damage the needle before use.   Δ
• To reduce the risk of unexpected needle sticks, never put the inner needle cap back on the needle.   Δ

Giving the airshot before each injection

Before each injection small amounts of air may collect in the cartridge during normal use. To avoid injecting air and to ensure proper dosing:

Turn the dose selector to select 2 units (see diagram E). E.

Hold your NovoLog FlexPen with the needle pointing up. Tap the cartridge gently with your finger a few times to make any air bubbles collect at the top of the cartridge (see diagram F). F.

Keep the needle pointing upwards, press the push-button all the way in (see diagram G). The dose selector returns to 0. G.

A drop of insulin should appear at the needle tip. If not, change the needle and repeat the procedure no more than 6 times.

If you do not see a drop of insulin after 6 times, do not use the NovoLog FlexPen and contact Novo Nordisk at 1-800-727-6500.

A small air bubble may remain at the needle tip, but it will not be injected.

Selecting your dose

Check and make sure that the dose selector is set at 0.

Turn the dose selector to the number of units you need to inject. The pointer should line up with your dose. H.

The dose can be corrected either up or down by turning the dose selector in either direction until the correct dose lines up with the pointer (see diagram H). When turning the dose selector, be careful not to press the push-button as insulin will come out.

You cannot select a dose larger than the number of units left in the cartridge.

You will hear a click for every single unit dialed. Do not set the dose by counting the number of clicks you hear.

• Δ Do not use the cartridge scale printed on the cartridge to measure your dose of insulin.  

Giving the injection

Do the injection exactly as shown to you by your healthcare provider. Your healthcare provider should tell you if you need to pinch the skin before injecting.

Insert the needle into your skin. I.

Inject the dose by pressing the push-button all the way in until the 0 lines up with the pointer (see diagram I). Be careful only to push the button when injecting.

Turning the dose selector will not inject insulin.

Keep the needle in the skin for at least 6 seconds, and keep the push-button pressed all the way in until the needle has been pulled out from the skin (see diagram J). This will make sure that the full dose has been given. J.

You may see a drop of NovoLog at the needle tip. This is normal and has no effect on the dose you just received. If blood appears after you take the needle out of your skin, press the injection site lightly with a finger. Do not rub the area.

After the injection

Recapping can lead to a needle stick injury.  Remove the needle from the NovoLog FlexPen after each injection. This helps to prevent infection, leakage of insulin, and will help to make sure you inject the right dose of insulin. Do not recap the needle.

• Put the needle and any empty NovoLog FlexPen or any used NovoLog FlexPen still containing insulin in a sharps container or some type of hard plastic or metal container with a screw top such as a detergent bottle or empty coffee can. These containers should be sealed and thrown away the right way. Check with your healthcare provider about the right way to throw away used syringes and needles.  There may be local or state laws about how to throw away used needles and syringes. Do not throw away used needles and syringes in household trash or recycling bins.   Δ

The NovoLog FlexPen prevents the cartridge from being completely emptied. It is designed to deliver 300 units.

. Put the pen cap on the NovoLog FlexPen and store the NovoLog FlexPen without the needle attached (see diagram K). K

L Function Check

If your NovoLog FlexPen is not working the right way, follow the steps below:

• Screw on a new NovoFine needle. •
• Remove the big outer needle cap and the inner needle cap. •
• Do an airshot as described in "Giving the airshot before each injection". •
• Put the big outer needle cap onto the needle. Do not put on the inner needle cap. •
• Turn the dose selector so the dose indicator window shows 20 units. •
• Hold the NovoLog FlexPen so the needle is pointing down. •
• Press the push-button all the way in. •

The insulin should fill the lower part of the big outer needle cap (see diagram L). If the NovoLog FlexPen has released too much or too little insulin, do the function check again. If the same problem happens again, do not use your NovoLog FlexPen and contact Novo Nordisk at 1-800-727-6500.

Maintenance

Your FlexPen is designed to work accurately and safely. It must be handled with care. Avoid dropping your FlexPen as it may damage it. If you are concerned that your FlexPen is damaged, use a new one. You can clean the outside of your FlexPen by wiping it with a damp cloth. Do not soak or wash your FlexPen as it may damage it. Do not refill your FlexPen.

Remove the needle from the NovoLog FlexPen after each injection. This helps to ensure sterility, prevent leakage of insulin, and will help to make sure you inject the right dose of insulin for future injections. Δ

Be careful when handling used needles to avoid needle sticks and transfer of infectious diseases. Δ

Keep your NovoLog FlexPen and needles out of the reach of children. Δ

Use NovoLog FlexPen as directed to treat your diabetes. Needles and NovoLog FlexPen must not be shared. Δ

Always use a new needle for each injection. Δ

Novo Nordisk is not responsible for harm due to using this insulin pen with products not recommended by Novo Nordisk. Δ

As a precautionary measure, always carry a spare insulin delivery device in case your NovoLog FlexPen is lost or damaged. Δ

Remember to keep the disposable NovoLog FlexPen with you. Do not leave it in a car or other location where it can get too hot or too cold. Δ