Hydrochlorothiazide 25 MG Oral Tablet
INDICATIONS AND USAGE Hydrochlorothiazide tablets are indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Hydrochlorothiazide tablets have also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure. Hydrochlorothiazide tablets are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. Use in Pregnancy Routine use of diuretics during normal pregnancy is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy and there is no satisfactory evidence that they are useful in the treatment of toxemia. Edema during pregnancy may arise from pathologic causes or from the physiologic and mechanical consequences of pregnancy. Thiazides are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy (see PRECAUTIONS, Pregnancy ). Dependent edema in pregnancy, resulting from restriction of venous return by the gravid uterus, is properly treated through elevation of the lower extremities and use of support stockings. Use of diuretics to lower intravascular volume in this instance is illogical and unnecessary. During normal pregnancy there is hypervolemia which is not harmful to the fetus or the mother in the absence of cardiovascular disease. However, it may be associated with edema, rarely generalized edema. If such edema causes discomfort, increased recumbency will often provide relief. Rarely this edema may cause extreme discomfort which is not relieved by rest. In these instances, a short course of diuretic therapy may provide relief and be appropriate.
Heritage Pharmaceuticals Inc.
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HOW SUPPLIED Hydrochlorothiazide tablets, USP 12.5 mg and 25 mg are available as light orange colored, round, flat face, beveled edge, uncoated tablets. Hydrochlorothiazide tablets, USP 50 mg are available as white to off-white colored round, flat face, beveled edge uncoated tablets. 12.5 mg Each tablet contains 12.5 mg hydrochlorothiazide, USP and is debossed with 'I' and '27' on one side and plain on the other side. NDC 23155-137-16 Bottles of 10 NDC 23155-137-01 Bottles of 100 NDC 23155-137-10 Bottles of 1000 25 mg Each tablet contains 25 mg hydrochlorothiazide, USP and is debossed with ‘HP’ above the bisect and ‘47’ below the bisect on one side and plain on the other side. NDC 23155-047-16 Bottles of 10 NDC 23155-047-01 Bottles of 100 NDC 23155-047-10 Bottles of 1000 50 mg Each tablet contains 50 mg hydrochlorothiazide, USP and is debossed with 'HP' above the bisect and '46' below the bisect on one side and plain on the other side. NDC 23155-046-16 Bottles of 10 NDC 23155-046-01 Bottles of 100 NDC 23155-046-10 Bottles of 1000 PHARMACIST: Dispense in a well-closed container as defined in the USP. Use child-resistant closure (as required). Store at 20° – 25°C (68 – 77°F) [See USP Controlled Room Temperature]. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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