Chlorthalidone 25 MG Oral Tablet
INDICATIONS AND USAGE Diuretics such as chlorthalidone are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. Chlorthalidone tablets are indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis and corticosteroid and estrogen therapy. Chlorthalidone tablets have also been found useful in edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis and chronic renal failure. Usage in Pregnancy The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy and there is no satisfactory evidence that they are useful in the treatment of developed toxemia. Edema during pregnancy may arise from pathologic causes or from the physiologic and mechanical consequences of pregnancy. Chlorthalidone tablets are indicated in pregnancy when edema is due to pathologic causes, just as it is in the absence of pregnancy (however, see PRECAUTIONS , below). Dependent edema in pregnancy, resulting from restriction of venous return by the expanded uterus, is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy that is harmful to neither the fetus nor the mother (in the absence of cardiovascular disease), but that is associated with edema, including generalized edema, in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances, this edema may cause extreme discomfort that is not relieved by rest. In these cases, a short course of diuretics may provide relief and be appropriate.
amneal pharmaceuticals llc
ROUND YELLOW AN 247
AN 247 ROUND YELLOW
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HOW SUPPLIED
CHLORTHALIDONE Tablets USP, 25 mg , are supplied as light yellow to yellow colored mosaic appearance, round shaped tablets debossed with “AN” and “247” on one side and plain on the other side. They are available as follows: Bottles of 30 : NDC 65162-247-03 Bottles of 90 : NDC 65162-247-09
CHLORTHALIDONE Tablets USP, 50 mg , are supplied as light green to green colored mosaic appearance, round shaped tablets debossed with “AN” and “250” on either side of the score on one side and plain on the other side. They are available as follows: Bottles of 30 : NDC 65162-250-03 Bottles of 90 : NDC 65162-250-09 Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Protect from light. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.
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