Carbidopa 25 MG Levodopa 100 MG Oral Tablet

INDICATIONS AND USAGE Carbidopa and levodopa tablets, USP are indicated in the treatment of Parkinson's disease, post-encephalitic parkinsonism, and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication. Carbidopa allows patients treated for Parkinson's disease to use much lower doses of levodopa. Some patients who responded poorly to levodopa have improved on carbidopa and levodopa tablets. This is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous system. Carbidopa has not been shown to enhance the intrinsic efficacy of levodopa. Carbidopa may also reduce nausea and vomiting and permit more rapid titration of levodopa.

mayne pharma inc.

FDA Reported Adverse Reactions
`[1] drug ineffective` `[2] adverse drug reaction` `[3] toxicity to various agents` `[4] completed suicide` `[5] drug abuse` `[6] off label use` `[7] nausea` `[8] death` `[9] headache` `[10] application site pruritus`

4 years ago

ROUND YELLOW M 721

HOW SUPPLIED

CARBIDOPA AND LEVODOPA Tablets, USP are supplied as follows: 10 mg/100 mg — Each mottled blue, round flat bevelled tablet, plain on one side, engraved with "m" above the score and "711" below the score contains 10 mg of Carbidopa, USP and 100 mg of Levodopa, USP and is supplied in bottles of 100 (NDC 51862-855-01) and 500 (NDC 51862-855-05). 25 mg/100 mg — Each mottled yellow, round flat bevelled tablet, plain on one side, scored on the other side, engraved with "m" above the score and "721" below the score contains 25 mg of Carbidopa, USP and 100 mg of Levodopa, USP and is supplied in bottles of 100 (NDC 51862-856-01), 500 (NDC 51862-856-05), and 1000 (NDC 51862-856-10). 25 mg/250 mg — Each mottled blue, round flat bevelled tablet, plain on one side, scored on the other side, engraved with "m" above the score and "731" below the score contains 25 mg of Carbidopa, USP and 250 mg of Levodopa, USP and is supplied in bottles of 100 (NDC 51862-858-01), 500 (NDC 51862-858-05), and 1000 (NDC 51862-858-10). Storage and Handling Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F) [see USP Controlled Room Temperature]. Protect from light and moisture. Dispense in a tightly closed, light-resistant container.

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Mayne Pharma Inc.

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